Written By: Team Pharmacally
Reviewed By: Dr. Seema Satbhai, BAMS, MPH, PhD-Public Health
Suicide is a complex health and social issue affected by biological, psychological, social, and environmental factors. Mental health conditions such as depression, substance use disorders, and anxiety are major risk factors, but suicide is also strongly linked to social elements like poverty, unemployment, violence, and conflict. Chronic illnesses, pain disorders, and disability can also further increase vulnerability. Because of this wide range of influences, suicide cannot be viewed only as an individual problem but as a broader public health challenge that affects families, communities, and health systems.
To understand the global scale of this issue, the World Health Organization (WHO) published Suicide Worldwide in 2021: Global Health Estimates in September 2025 The report provides updated and uniform statistics on suicide mortality across countries, age groups, and income levels. It highlights where progress has been made, where gaps remain, and how current trends align with the global targets for reducing suicide deaths.
In 2021, about 727,000 people died by suicide, accounting for 1.1% of all deaths worldwide. This means suicide claimed more lives than malaria, HIV/AIDS, breast cancer, or armed conflict.
Despite being preventable, suicide continues to be a leading cause of death, especially among young people.
Reducing suicide is part of the United Nations Sustainable Development Goals (SDG 3.4.2) and remains a top priority in the WHO Comprehensive Mental Health Action Plan 2013–2030
Impact of COVID-19 on Suicide Estimates during 2020-2021
The COVID-19 pandemic disrupted health and reporting systems in many countries. As a result, the availability and quality of mortality data for 2020 and 2021 were affected. Civil registration and vital statistics systems in several regions faced delays and underreporting, making it harder to capture suicide deaths accurately.
WHO notes that the suicide numbers for these years are likely underestimated. This means that part of the decline observed in global suicide rates may reflect data gaps rather than real reductions. For this reason, the 2021 estimates should be interpreted with caution, and continued investment in stronger death registration systems is essential for reliable monitoring.
Global Burden of Suicide
Global suicide rate (2021): 8.9 per 100,000 populations
Sex differences: Men – 12.3 per 100,000; Women – 5.6 per 100,000. Suicide rates were 2.2 times higher in men
Age differences: More than half (56%) of suicides occurred before age 50. Suicide was the third leading cause of death in people aged 15–29 and the second leading cause among adolescent girls (15–19 years)
Geography: Rates ranged from less than 1 to nearly 40 per 100,000 across countries
Regional Patterns
Higher-than-average suicide rates were observed in:
Africa: 11.5 per 100,000
Europe: 10.1 per 100,000
South-East Asia: 10.1 per 100,000
Americas: 9.2 per 100,000
Lowest rate: Eastern Mediterranean Region (4.0 per 100,000).
Western Pacific: 7.5 per 100,000.
Income levels
High-income countries had the highest age-standardized suicide rate (11.8 per 100,000), mainly driven by male deaths. Low-income countries had a marginally lower rate (10.5 per 100 000), lower-middle-income and upper-middle-income countries (9.4 per 100 000 and 7.0 per 100 000 respectively)
Low- and middle-income countries accounted for 73% of all suicides.
Long-Term Trends
Between 2000 and 2021, the global age-standardized suicide rate declined by 35%. However, progress was uneven:
Declines: Western Pacific (–50%), Europe (–48%), Eastern Mediterranean (–30%), South-East Asia (–26%), Africa (–3%).
Increase: Americas (+17%).
At the current pace, the world will achieve only a 12% reduction by 2030, far from the SDG target of one-third
Data Quality Challenges
Only 60 of 183 WHO member states had high-quality death registration systems.
Most low- and middle-income countries relied on modeling due to incomplete or unreliable records.
Suicide is often under-reported because of stigma and inconsistent death certification
Suicide Prevention: WHO’s LIVE LIFE Framework
The WHO emphasizes that suicide is preventable. Its LIVE LIFE implementation guide recommends four key evidence-based actions
Limit access to means of suicide (e.g., pesticides, firearms, barriers at hotspots).
Promote responsible media reporting to avoid harmful imitation and highlight recovery stories.
Foster socio-emotional life skills in adolescents, through school-based and community programs.
Ensure early identification, assessment, and follow-up for people at risk or affected by suicidal behavior.
These must be supported by six cross-cutting pillars: strong surveillance, multisectoral collaboration, awareness campaigns, capacity building, sustainable financing, and community engagement.
Emerging Concerns beyond the Report
However the WHO estimates focus on global patterns and established risk factors, additional factors are also relevant, these includes
Digital media and gaming influence: Online platforms and certain games have been reported to expose children and adolescents to harmful content, including tasks or challenges that encourage risky or self-harming behavior. The data is still evolving in this aspects; the influence of digital environments on vulnerable youth especially adolescents is a growing concern for mental health and suicide prevention.
Climate-related stress: Environmental instability adds another layer of risk. In India and other agricultural economies, farmer suicides have been linked to crop failures caused by inconsistent rainfall, droughts, or flooding. Climate stress is an indirect but powerful cause of distress, debt, and hopelessness in affected populations.
These factors underline the need for suicide prevention to be adaptable, multidisciplinary, and responsive to new challenges beyond traditional mental health care.
Conclusion
The 2021 WHO estimates confirm that suicide remains a major public health problem worldwide. In that year, 727,000 deaths were recorded, representing 1.1% of all global deaths.
There has been a 35% decline in age-standardized suicide rates since 2000; the decline is too slow to reach the target of cutting suicide deaths by one-third by 2030. If current trends continue, only a 12% reduction will be achieved.
The data highlight important inequalities. Suicide rates are consistently higher in men, in young people, and in low- and middle-income countries. Some regions, such as the Americas, have seen rising rates despite global progress. Weaknesses in death registration systems, underreporting, and stigma continue to limit the accuracy of surveillance, especially in resource-limited settings.
From a public health perspective, these findings emphasis the necessity of boosting effective prevention strategies. WHO’s LIVE LIFE framework outlines priority interventions that can be implemented at national and community levels that includes limiting access to means of suicide, improving media reporting standards, promoting socio-emotional skills in adolescents, and ensuring early identification and follow-up for people at risk.
Strengthening surveillance systems, improving data quality, and ensuring sustained multisectoral action are necessary to accelerate progress. Suicide is preventable, but prevention requires integrating these measures into routine public health planning. Without stronger commitment and expanded implementation, the global target for 2030 will not be achieved, and preventable deaths will continue to impose a significant burden on families, communities, and health systems.
Glossary of Abbreviations and Terminologies
- WHO – World Health Organization
- SDG – Sustainable Development Goal
- SDG 3.4.2 – Indicator under SDG target 3.4: suicide mortality rate
- LMICs – Low- and Middle-Income Countries
- HICs – High-Income Countries
- CRVS – Civil Registration and Vital Statistics
- mhGAP – Mental Health Gap Action Programme
- GBD – Global Burden of Disease Study
- LIVE LIFE – WHO’s implementation guide for suicide prevention (Limit access to means, Interact with media, Value life skills in youth, Early identify and follow-up)
· Age-Standardized Suicide Rate
The age-standardized suicide rate is the suicide rate per 100,000 people, adjusted to a standard age distribution.
· High-Quality Death Registration Systems
A high-quality death registration system (also called a Civil Registration and Vital Statistics, CRVS, system) is one that records all deaths in a population with accurate details on cause, age, and sex.
Reference
Suicide worldwide in 2021: global health estimates. Geneva: World Health Organization; 2025. Licence: CC BY-NC-SA 3.0 IGO.

